JetBlue will move from Terminal A to the larger Terminal C at San Juan's Luis Munoz Airport at the end of May.
JetBlue launched service to Puerto Rico in May 2002 and now has flights from seven U.S. gateways to San Juan, Aguadilla and Ponce.
The carrier begins Newark-San Juan service on April 25 and West Palm Beach-San Juan service on May 15.
JetBlue also has filed an application with the Department of Transportation for nonstop service from Washington Reagan National Airport to San Juan.
Follow Gay Nagle Myers on Twitter @gnmtravelweekly.