Hotels Melia's first ME hotel in U.S. to open in Miami in 2015 By Danny King / August 27, 2014 Share 1 -- Spain-based hotelier Melia Hotels International will open its first U.S. hotel under its ME by Melia brand in Miami next spring. ME Miami will open in what's now Casa Moderna on Miami's Biscayne Boulevard. The hotel will have 129 rooms as well as more than 5,000 square feet of food and beverage space. Melia Hotels, which has more than 350 hotels across 39 countries, oversees six ME-branded hotels in locations such as London, Madrid and Cancun. Follow Danny King on Twitter @dktravelweekly.