A rendering of the courtyard at the Rosewood Sao Paulo.
Rosewood Hotels & Resorts plans to open the Rosewood Sao Paulo in Brazil in 2018, the company's first property in South America.
The hotel, which will feature 151 guestrooms and 114 owners' suites, will be housed in a landmark complex that was formerly a maternity hospital in the center of the city.
The property will include two restaurants, a bar and a caviar lounge, two pools, a spa and a wedding chapel.
Pritzker Prize-winning architect Jean Nouvel, designer Philippe Starck and Brazilian artists Beatriz Milhazes and Saint-Clare Cemin will collaborate on the project.
Rosewood's move into South America follows the recent opening of Rosewood Beijing, the company's first hotel in China. It is part of a global expansion for Rosewood, which has announced 13 hotels under development, including Hotel de Crillon, A Rosewood Hotel in Paris. Rosewood will take over management of the iconic Paris property in 2016 following major renovations.