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Santo Domingo, Dominican Republic Cruises


Santo Domingo, Dominican Republic Cruise Sailing Schedule


Use the Santo Domingo cruise schedule calendar below to find a Santo Domingo cruise sailing by destination, cruise line, or ship.

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Prices represent the lowest available price for a given sailing date, area, and/or month. All prices USD.

Upcoming Santo Domingo Cruise Itineraries


Select an upcoming Santo Domingo cruise itinerary list below to find a Santo Domingo sailing itinerary by destination, line, or ship.

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Sea Cloud Cruises

InteriorOceanviewBalconySuite
02/16/201510 Night Caribbean Cruise

on the Sea Cloud Cruises Sea Cloud departing from Santo Domingo, Dominican Republic

Contact cruise line for pricing & availability

Cruise Lines Cruising to Santo Domingo


Cruise Ships Cruising to Santo Domingo


Santo Domingo travel42 Port of Call Guide


The Dominican Republic's capital and largest city, Santo Domingo is the oldest city in the Americas. It was founded in 1498 and was Spain's first colonial headquarters in the New World.

Today the country’s largest metropolitan area and home to more than 2.9 million people, Santo Domingo is the largest city in the Caribbean and is the country's economic and political hub, as well as one of the Caribbean's top business centers. It has the island's most exciting nightclubs, restaurants and shopp...

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