Orient Express has debuted its second hotel with the opening of the Orient Express Venezia at Palazzo Dona Giovannelli in Venice's Cannaregio district.
Housed within a 15th-century palazzo, the property features 47 accommodations, including residences. The hotel's interiors showcase elements like restored murals, bespoke Murano chandeliers and marble fireplaces.
The property offers three food and beverage outlets, including Heinz Beck Venezia, a fine-dining concept from the three-Michelin-starred chef; La Casati, an all-day dining restaurant with a private garden; and the Wagon Bar, an art deco-inspired lounge.
The hotel is also home to Salone Vittoria, an event space that guests can access via boat.
The Venice opening is part of Orient Express' broader expansion push. Accor, which took full ownership of the brand in 2022, has been building out an ultraluxe portfolio that spans hotels, trains and yachts.
The Venice hotel follows the opening of the Orient Express La Minerva in Rome last year.
The brand also debuted a uxury train, La Dolce Vita Orient Express, in 2025, with its first sailing yacht, the Orient Express Corinthian, set to debut this summer in the Mediterranean.