Itinerary for December 06, 2026 Departure Day Date Location Port of Call Guide 1Sunday, 12/06/2026Depart from BalboaBalboa, Panama2Monday, 12/07/2026Portobelo / Panama Canal Transit Portobelo, Panama3Tuesday, 12/08/2026Gatún Lake / Panama Canal Transit 4Wednesday, 12/09/2026Pearl Islands 5Thursday, 12/10/2026Pearl Islands 6Friday, 12/11/2026Playa Muerto, Darién National Park 7Saturday, 12/12/2026Punta Patiño Nature Reserve 8Sunday, 12/13/2026Arrive at ColonColon, Panama Check Cruise Availability Total guests should not exceed 5 passengers. Adults: (ages 12-54) 0 1 2 3 4 5 Seniors: (ages 55 or older) 0 1 2 3 4 5 Kids: (ages 2-11) 0 1 2 3 4 5 Infants: (under 2) 0 1 2 3 4 5 Kid 1 Age: (at time of cruise) 0 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 Kid 2 Age: (at time of cruise) 0 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 Kid 3 Age: (at time of cruise) 0 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 Kid 4 Age: (at time of cruise) 0 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 Kid 5 Age: (at time of cruise) 0 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 US Resident? Need Airfare? Search Availability State/Province of Residence: Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware District of Columbia Florida Georgia Hawaii Idaho Illinois Indiana Iowa Kansas Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Mississippi Missouri Montana Nebraska Nevada New Hampshire New Jersey New Mexico New York North Carolina North Dakota Ohio Oklahoma Oregon Pennsylvania Puerto Rico Rhode Island South Carolina South Dakota Tennessee Texas Utah Vermont Virgin Islands Virginia Washington West Virginia Wisconsin Wyoming Alberta British Columbia Manitoba New Brunswick Newfoundland Northwest Territory Nova Scotia Ontario Prince Edward Island Quebec Saskatchewan St. Pierre and Miquelon Yukon Territory Departure City/Airport Code: Akron, OH (CAK) Albany, GA (ABY) Albany, NY (ALB) Albuquerque, NM (ABQ) Allentown, PA (ABE) Altoona, PA (AOO) Amarillo, TX (AMA) Anchorage, AK (ANC) Anderson, SC (AND) Appleton, WI (ATW) Asheville, NC (AVL) Atlanta, GA (ATL) Atlantic City, NJ (ACY) Augusta, GA (AGS) Austin, TX (AUS) Bakersfield, CA (BFL) Baltimore, MD (BWI) Bangor, ME (BGR) Baton Rouge, LA (BTR) Beaumont / Port Arthur, TX (BPT) Beckley, WV (BKW) Bellingham, WA (BLI) Billings, MT (BIL) Binghamton, NY (BGM) Birmingham, AL (BHM) Bismarck, ND (BIS) Bloomington, IL (BMI) Bluefield, WV (BLF) Boise, ID (BOI) Boston, MA (BOS) Bozeman, MT (BZN) Bradford-Warren, NY (BFD) Brainerd, MN (BRD) Buffalo, NY (BUF) Burbank, CA (BUR) Burlington, VT (BTV) Butte, MT (BTM) Cedar Rapids, IA (CID) Central Wisconsin Aprt, WI (CWA) Champaign / Urbana, IL (CMI) Charleston, SC (CHS) Charleston, WV (CRW) Charlotte, NC (CLT) Charlottesville, VA (CHO) Chattanooga, TN (CHA) Cheyenne, WY (CYS) Chicago - Midway, IL (MDW) Chicago - Ohare, IL (ORD) Cincinnati, OH (CVG) Cleveland, OH (CLE) Colorado Springs, CO (COS) Columbia, MO (COU) Columbia, SC (CAE) Columbus, GA (CSG) Columbus, OH (CMH) Corpus Christi, TX (CRP) Dallas - Ft. Worth, TX (DFW) Danville, VA (DAN) Dayton, OH (DAY) Daytona Beach, FL (DAB) Denver, CO (DEN) Des Moines, IA (DSM) Detroit, MI (DTW) Dubois, PA (DUJ) Duluth, MN (DLH) El Paso, TX (ELP) Elmira, NY (ELM) Erie, PA (ERI) Escanaba, MI (ESC) Eugene, OR (EUG) Evansville, IN (EVV) Fairbanks, AK (FAI) Fargo, ND (FAR) Fayetteville, NC (FAY) Flagstaff, AZ (FLG) Flint, MI (FNT) Florence, SC (FLO) Fort Myers, FL (RSW) Fort Smith, AR (FSM) Fort Walton Beach, FL (VPS) Fresno, CA (FAT) Ft. Lauderdale, FL (FLL) Ft. Wayne, IN (FWA) Gainesville, FL (GNV) Grand Forks, ND (GFK) Grand Junction, CO (GJT) Grand Rapids, MI (GRR) Great Falls, MT (GTF) Green Bay, WI (GRB) Greensboro, NC (GSO) Greenville, NC (PGV) Greenville, SC (GSP) Hagerstown, MD (HGR) Haines, AK (HNS) Harlingen, TX (HRL) Harrisburg, PA (MDT) Hartford, CT (BDL) Helena, MT (HLN) Hickory, NC (HKY) Hilo, HI (ITO) Honolulu, HI (HNL) Houston - Hobby, TX (HOU) Houston - Intercontinental, TX (IAH) Huntington, WV (HTS) Huntsville, AL (HSV) Indianapolis, IN (IND) Islip, NY (ISP) Ithaca, NY (ITH) Jackson, MS (JAN) Jacksonville, FL (JAX) Jacksonville, NC (OAJ) Johnstown, PA (JST) Joplin, MO (JLN) Juneau, AK (JNU) Kalamazoo, MI (AZO) Kalispell, MT (FCA) Kansas City, MO (MCI) Ketchikan, AK (KTN) Key West, FL (EYW) Kinston, NC (ISO) Knoxville, TN (TYS) Kona, HI (KOA) La Cross, WI (LSE) Lafayette, LA (LFT) Lancaster, PA (LNS) Lansing, MI (LAN) Las Vegas, NV (LAS) Lexington, KY (LEX) Lihue, HI (LIH) Lincoln, NE (LNK) Little Rock, AR (LIT) Long Beach, CA (LGB) Los Angeles, CA (LAX) Louisville, KY (SDF) Lubbock, TX (LBB) Lynchburg, VA (LYH) Macon, GA (MCN) Madison, WI (MSN) Manchester, NH (MHT) Mason City, IA (MCW) Maui, HI (OGG) Maui - Lahaina, HI (HKP) Mcallen, TX (MFE) Medford, OR (MFR) Melbourne, FL (MLB) Memphis, TN (MEM) Miami, FL (MIA) Midland/Odessa, TX (MAF) Milwaukee, WI (MKE) Minneapolis, MN (MSP) Minot, ND (MOT) Missoula, MT (MSO) Mobile, AL (MOB) Moline, IL (MLI) Molokai, HI (MKK) Monroe, LA (MLU) Monterey, CA (MRY) Montgomery, AL (MGM) Morgantown, WV (MGW) Myrtle Beach, SC (MYR) Naples, FL (APF) Nashville, TN (BNA) New Bern, NC (EWN) New Haven, CT (HVN) New Orleans, LA (MSY) New York - JFK, NY (JFK) New York - Laguardia, NY (LGA) Newark, NJ (EWR) Newburgh, NY (SWF) Newport News, VA (PHF) Norfolk, VA (ORF) Oakland, CA (OAK) Oklahoma City, OK (OKC) Omaha, NE (OMA) Ontario, CA (ONT) Orlando, FL (MCO) Oxnard, CA (OXR) Palm Springs, CA (PSP) Panama City, FL (PFN) Pasco, WA (PSC) Pellston, MI (PLN) Pensacola, FL (PNS) Peoria, IL (PIA) Philadelphia, PA (PHL) Phoenix, AZ (PHX) Pittsburgh, PA (PIT) Plattsburg, NY (PLB) Port Canaveral, FL (PCN) Port Charlotte, FL (FMY) Portland, ME (PWM) Portland, OR (PDX) Providence, RI (PVD) Punta Gorda, FL (PGD) Quincy, IL (UIN) Raleigh/Durham, NC (RDU) Rapid City, SD (RAP) Reading, PA (RDG) Reno, NV (RNO) Richmond, VA (RIC) Roanoke, VA (ROA) Rochester, MN (RST) Rochester, NY (ROC) Rockford, IL (RFD) Rocky Mount, NC (RWI) Sacramento, CA (SMF) Saginaw, MI (MBS) Salisbury, MD (SBY) Salt Lake City, UT (SLC) San Antonio, TX (SAT) San Diego, CA (SAN) San Francisco, CA (SFO) San Jose, CA (SJC) San Juan, PR (SJU) San Luis Obispo, CA (SBP) Santa Ana, CA (SNA) Santa Barbara, CA (SBA) Sarasota / Bradenton, FL (SRQ) Savannah, GA (SAV) Seattle/Tacoma, WA (SEA) Shreveport, LA (SHV) Sioux City, IA (SUX) Sioux Falls, SD (FSD) Sitka, AK (SIT) Skagway, AK (SGY) South Bend, IN (SBN) Spokane, WA (GEG) Springfield, IL (SPI) Springfield, MO (SGF) St. Louis, MO (STL) St. Petersburg, FL (PIE) State College, PA (SCE) Syracuse, NY (SYR) Tallahassee, FL (TLH) Tampa, FL (TPA) Taylorsville, NC (TYL) Toledo, OH (TOL) Tri-Cities, TN (TRI) Tucson, AZ (TUS) Tulsa, OK (TUL) Ufville, NC (UFT) Valdosta, GA (VLD) Washington - Dulles, DC (IAD) Washington - National, DC (DCA) Waterloo, IA (ALO) West Palm Beach, FL (PBI) Westchester County, NY (HPN) Wichita, KS (ICT) Wilkes-Barre / Scranton, PA (AVP) Wilmington, NC (ILM) Worcester, MA (ORH) Calgary, AB (YYC) Castlegar, CA (YCG) Charlottetown, PE (YYG) Edmonton, AB (YEG) Fredericton, NB (YFC) Halifax, NS (YHZ) Moncton, NB (YQM) Montreal, PQ (YUL) Montreal/Mirabel, PQ (YMX) OtYTIa, ON (YOW) Quebec, QB (YQB) Regina, SK (YQR) Saskatoon, SK (YXE) St. John - New Brunswick, NB (YSJ) St. Johns, NF (YYT) Sydney, NS (YQY) Thunder Bay, ON (YQT) Toronto, ON (YYZ) Vancouver, BC (YVR) Victoria, BC (YYJ) Windsor, ON (YQG) Winnipeg, MN (YWG) Searching Cruise for Available Rooms & Rates... Other 7 Night South American Cruise Itineraries on the Natl Geographic Quest Departing Interior Oceanview Balcony Suite Dec 6, 2026-$7,532$9,946$10,988Dec 13, 2026-$7,532$9,946$10,988Jan 29, 2027-$7,761$10,460$11,559Nov 5, 2027-$7,532$9,946$10,988Jan 29, 2028-$7,532$9,946$10,988Mar 9, 2028-$7,532$9,946$10,988Mar 16, 2028-$7,532$9,946$10,988 Departing from Balboa, PanamaDeparture Date 12/06/2026 OCG Class Expedition Departing 12/06/2026 Interior-Oceanviewfrom $7,532Balconyfrom $9,946Suitefrom $10,988 Check Availability