Select an upcoming Siem Reap cruise itinerary list below to find a Siem Reap sailing itinerary by destination, line, or ship. Search All Cruises Pandaw River Cruises01/30/20213 Night Southeast Asia Cruise Phnom Penh and Siem Reapon the Pandaw River Cruises Mekong Pandaw departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability01/30/20217 Night Southeast Asia Cruise Classic Mekongon the Pandaw River Cruises Mekong Pandaw departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability01/31/20217 Night Southeast Asia Cruise Classic Mekongon the Pandaw River Cruises Tonle Pandaw departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability02/13/20213 Night Southeast Asia Cruise Phnom Penh and Siem Reapon the Pandaw River Cruises Mekong Pandaw departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability02/13/20217 Night Southeast Asia Cruise Classic Mekongon the Pandaw River Cruises Mekong Pandaw departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability02/14/20217 Night Southeast Asia Cruise Classic Mekongon the Pandaw River Cruises Tonle Pandaw departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability02/27/20213 Night Southeast Asia Cruise Phnom Penh and Siem Reapon the Pandaw River Cruises Mekong Pandaw departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability02/27/20217 Night Southeast Asia Cruise Classic Mekongon the Pandaw River Cruises Mekong Pandaw departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability02/28/20217 Night Southeast Asia Cruise Classic Mekongon the Pandaw River Cruises Tonle Pandaw departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability03/13/20213 Night Southeast Asia Cruise Phnom Penh and Siem Reapon the Pandaw River Cruises Mekong Pandaw departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability03/13/20217 Night Southeast Asia Cruise Classic Mekongon the Pandaw River Cruises Mekong Pandaw departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability03/14/20217 Night Southeast Asia Cruise Classic Mekongon the Pandaw River Cruises Tonle Pandaw departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability03/27/20213 Night Southeast Asia Cruise Phnom Penh and Siem Reapon the Pandaw River Cruises Mekong Pandaw departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability03/27/20217 Night Southeast Asia Cruise Classic Mekongon the Pandaw River Cruises Mekong Pandaw departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability03/28/20217 Night Southeast Asia Cruise Classic Mekongon the Pandaw River Cruises Tonle Pandaw departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability08/28/20217 Night Southeast Asia Cruise Classic Mekongon the Pandaw River Cruises Mekong Pandaw departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability09/11/20217 Night Southeast Asia Cruise Classic Mekongon the Pandaw River Cruises Mekong Pandaw departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability09/25/20217 Night Southeast Asia Cruise Classic Mekongon the Pandaw River Cruises Mekong Pandaw departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability10/16/20217 Night Southeast Asia Cruise Classic Mekongon the Pandaw River Cruises Tonle Pandaw departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability10/30/20217 Night Southeast Asia Cruise Classic Mekongon the Pandaw River Cruises Tonle Pandaw departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability11/13/20217 Night Southeast Asia Cruise Classic Mekongon the Pandaw River Cruises Tonle Pandaw departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability11/27/20217 Night Southeast Asia Cruise Classic Mekongon the Pandaw River Cruises Tonle Pandaw departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability12/25/20217 Night Southeast Asia Cruise Classic Mekongon the Pandaw River Cruises Tonle Pandaw departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability02/05/20227 Night Southeast Asia Cruise Classic Mekongon the Pandaw River Cruises Tonle Pandaw departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability02/19/20227 Night Southeast Asia Cruise Classic Mekongon the Pandaw River Cruises Tonle Pandaw departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availabilityScenic03/13/202110 Night Southeast Asia Cruise Luxury Mekong & Temple Discovery Cruiseon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability03/13/202112 Night Southeast Asia Cruise Treasures of the Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability03/16/20217 Night Southeast Asia Cruise Luxury Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability03/27/202110 Night Southeast Asia Cruise Luxury Mekong & Temple Discovery Cruiseon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability03/27/202112 Night Southeast Asia Cruise Treasures of the Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability03/30/20217 Night Southeast Asia Cruise Luxury Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability04/10/202110 Night Southeast Asia Cruise Luxury Mekong & Temple Discovery Cruiseon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability04/10/202112 Night Southeast Asia Cruise Treasures of the Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability04/13/20217 Night Southeast Asia Cruise Luxury Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability04/24/202110 Night Southeast Asia Cruise Luxury Mekong & Temple Discovery Cruiseon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability04/24/202112 Night Southeast Asia Cruise Treasures of the Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability04/27/20217 Night Southeast Asia Cruise Luxury Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability05/08/202110 Night Southeast Asia Cruise Luxury Mekong & Temple Discovery Cruiseon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability05/08/202112 Night Southeast Asia Cruise Treasures of the Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability05/11/20217 Night Southeast Asia Cruise Luxury Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability07/17/202110 Night Southeast Asia Cruise Luxury Mekong & Temple Discovery Cruiseon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability07/17/202112 Night Southeast Asia Cruise Treasures of the Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability07/20/20217 Night Southeast Asia Cruise Luxury Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability07/31/202110 Night Southeast Asia Cruise Luxury Mekong & Temple Discovery Cruiseon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability07/31/202112 Night Southeast Asia Cruise Treasures of the Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability08/03/20217 Night Southeast Asia Cruise Luxury Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability08/14/202110 Night Southeast Asia Cruise Luxury Mekong & Temple Discovery Cruiseon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability08/14/202112 Night Southeast Asia Cruise Treasures of the Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability08/17/20217 Night Southeast Asia Cruise Luxury Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability08/28/202110 Night Southeast Asia Cruise Luxury Mekong & Temple Discovery Cruiseon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability08/28/202112 Night Southeast Asia Cruise Treasures of the Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability08/31/20217 Night Southeast Asia Cruise Luxury Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability09/11/202110 Night Southeast Asia Cruise Luxury Mekong & Temple Discovery Cruiseon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability09/11/202112 Night Southeast Asia Cruise Treasures of the Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability09/14/20217 Night Southeast Asia Cruise Luxury Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability09/25/202110 Night Southeast Asia Cruise Luxury Mekong & Temple Discovery Cruiseon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability09/25/202112 Night Southeast Asia Cruise Treasures of the Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability09/28/20217 Night Southeast Asia Cruise Luxury Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability10/09/202110 Night Southeast Asia Cruise Luxury Mekong & Temple Discovery Cruiseon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability10/09/202112 Night Southeast Asia Cruise Treasures of the Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability10/09/202125 Night Southeast Asia Cruise Treasures of the Mekong & Mystical Irrawaddyon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuite---$32,49510/12/20217 Night Southeast Asia Cruise Luxury Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability10/23/202110 Night Southeast Asia Cruise Luxury Mekong & Temple Discovery Cruiseon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability10/23/202112 Night Southeast Asia Cruise Treasures of the Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability10/26/20217 Night Southeast Asia Cruise Luxury Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability11/06/202110 Night Southeast Asia Cruise Luxury Mekong & Temple Discovery Cruiseon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability11/06/202112 Night Southeast Asia Cruise Treasures of the Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability11/09/20217 Night Southeast Asia Cruise Luxury Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability11/20/202110 Night Southeast Asia Cruise Luxury Mekong & Temple Discovery Cruiseon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability11/20/202112 Night Southeast Asia Cruise Treasures of the Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability11/23/20217 Night Southeast Asia Cruise Luxury Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability12/04/202110 Night Southeast Asia Cruise Luxury Mekong & Temple Discovery Cruiseon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability12/04/202112 Night Southeast Asia Cruise Treasures of the Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability12/07/20217 Night Southeast Asia Cruise Luxury Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability12/18/202110 Night Southeast Asia Cruise Luxury Mekong & Temple Discovery Cruiseon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability12/18/202112 Night Southeast Asia Cruise Treasures of the Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability12/21/20217 Night Southeast Asia Cruise Luxury Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability01/01/202210 Night Southeast Asia Cruise Luxury Mekong & Temple Discovery Cruiseon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability01/01/202212 Night Southeast Asia Cruise Treasures of the Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability01/04/20227 Night Southeast Asia Cruise Luxury Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability01/15/202210 Night Southeast Asia Cruise Luxury Mekong & Temple Discovery Cruiseon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability01/15/202212 Night Southeast Asia Cruise Treasures of the Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability01/18/20227 Night Southeast Asia Cruise Luxury Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability01/29/202210 Night Southeast Asia Cruise Luxury Mekong & Temple Discovery Cruiseon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability01/29/202212 Night Southeast Asia Cruise Treasures of the Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability02/01/20227 Night Southeast Asia Cruise Luxury Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability02/12/202210 Night Southeast Asia Cruise Luxury Mekong & Temple Discovery Cruiseon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability02/12/202212 Night Southeast Asia Cruise Treasures of the Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability02/15/20227 Night Southeast Asia Cruise Luxury Mekongon the Scenic Scenic Spirit departing from Siem Reap, CambodiaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability