Cayman Airways will launch a Saturday nonstop from Miami to Cayman Brac on April 17.
A return flight from Cayman Brac will stop in Grand Cayman and operate five days a week.
"Cayman Airways, the Department of Tourism and the Sister Islands Tourism Association have worked to secure this crucial airlift as part of the growth and revitalization of the tourism industry," said Julianna O’Connor-Connolly, deputy premier and Sister Islands representative.