Air China will be suspending its direct Beijing-to-Honolulu route starting Aug. 27, the company announced in a statement.
China's flagship carrier said the decision was based on "network layout, capacity arrangement and other reasons."
In a statement on its website the airline said all purchased tickets for canceled flights will be refunded. The three-times-per-week Honolulu service reported a 66% load factor in 2018, roughly 10 percentage points lower than its routes to other U.S. cities, according to U.S. Department of Transportation data.
Last year, Hawaiian Airlines stopped operating its own nonstop service between Honolulu and Beijing.
The number of Chinese tourists arriving in the United States posted the first decline last year in 15 years, according to U.S. data, and in June Beijing issued a travel advisory warning Chinese tourists of risks involved with traveling to the United States, such as gun violence, robberies and thefts.