Air France will begin serving Las Vegas in the spring, flying three times weekly from April 14 to Oct. 24.
Air France will be the only carrier serving the route, using Airbus A350 aircraft with business, premium economy and economy cabins.
The carrier had previously flown Paris-Las Vegas only for the CES consumer electronic shows in January, a service it will again offer this year.
Las Vegas is Air France's 19th U.S. destination.