Cathay Pacific CEO Rupert Hogg has resigned in the wake of anti-government protests that roiled the airline and closed Hong Kong International Airport on Monday evening and Tuesday. 

"Recent events have called into question Cathay Pacific's commitment to flight safety and security and put our reputation and brand under pressure," Cathay Pacific chairman John Slosar said in statement Friday. "This is regrettable, as we have always made safety and security our highest priority. We therefore think it is time to put a new management team in place who can reset confidence and lead the airline to new heights."

A week ago, China's government told Cathay Pacific that airline employees who participated in the protests would not be allowed to fly to or from mainland China, reported the South China Morning Post. State-owned Air China Group is a significant stakeholder in Cathay Pacific.

The airport protests forced Cathay to cancel nearly 300 flights on Monday and Tuesday. During the airport unrest, Cathay threatened to fire employees who participated. 

On Wednesday, Cathay issued a statement that it had fired two pilots, including one who "misused company information" on a Monday flight. 

Cathay Pacific chief commercial officer Paul Loo also stepped down Friday. 

The company has replaced Hogg with Augustus Tang, CEO of Hong Kong Aircraft Engineering Co. Loo has been replaced by Ronald Lam, CEO of Cathay subsidiary and discount carrier Hong Kong Express. Lam will continue to head Hong Kong Express until a replacement is found, Cathay said.

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